A simple, rapid, accurate and precise, spectrophotometric method was developed for determination of mebeverine hydrochloride and its formulations i.e., Meb Sr and Colospa. In this method mebeverine hydrochloride shows absorbance maximum at different wavelength in different solvents, so absorbance was measured and the same wavelengths used for the estimation of mebeverine hydrochloride in respective solvents. Mebeverine hydrochloride obeys the beer lamberts’ law. Method was validated according to ICH guideline and carried out for analysis of mebeverine hydrochloride.
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